Description

Methyl 4-Amino-2,2-Dimethylbutanoate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in the form of a stable hydrochloride salt. This compound is critical for the synthesis of complex molecules, offering a protected amino acid ester moiety essential for peptide coupling and medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and complex organic molecules targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific functional groups into molecular scaffolds.
• Process Chemistry Development: Serves as a standardized starting material for scaling up API synthesis under current Good Manufacturing Practice (cGMP) conditions.
• Bioconjugation: Potential use in the modification of biomolecules, where its ester and amine functionalities can be leveraged for linking chemistries.
• Chemical Biology Probes: Can be incorporated into tool compounds for studying biological pathways and enzyme functions.

Basic Information

Product Name	Methyl 4-Amino-2,2-Dimethylbutanoate Hydrochloride
CAS No.	951160-35-3
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	4-Amino-2,2-dimethylbutanoic acid methyl ester hydrochloride; Methyl 4-amino-2,2-dimethylbutyrate hydrochloride; 2,2-Dimethyl-4-aminobutanoic acid methyl ester HCl; 4-Amino-2,2-dimethyl-butyric acid methyl ester hydrochloride; Butanoic acid, 4-amino-2,2-dimethyl-, methyl ester, hydrochloride; Methyl ester of 4-amino-2,2-dimethylbutanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-2,2-Dimethylbutanoate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality management standards to guarantee supply reliability for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.