Description

2,4-Dichloro-7-Sem-7H-Pyrrolo-[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted kinase inhibitors and other small-molecule therapeutics. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in cutting-edge drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and commercial route development for new APIs.
• Biochemical Research: Employed as a tool compound or precursor in biochemical assays to study enzyme function and cellular signaling pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules for client projects.

Basic Information

Item	Details
Product Name	2,4-Dichloro-7-Sem-7H-Pyrrolo-[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	950661-85-5
Molecular Formula	C9H5Cl2N3O2
Molecular Weight	258.06 g/mol
Synonyms	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 2,4-dichloro-; 950661-85-5; 2,4-Dichloro-7-aza-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; Pyrrolopyrimidine-5-carboxylic acid derivative; Kinase inhibitor intermediate; Heterocyclic carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-Sem-7H-Pyrrolo-[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.