Description

Piperidin-4-Yl-Pyrimidin-2-Yl-Aminehydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and production of kinase inhibitors, a major class of drugs for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological processes and enzyme functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug design methodologies.

Basic Information

Product Name	Piperidin-4-Yl-Pyrimidin-2-Yl-Aminehydrochloride
CAS No.	950649-10-2
Molecular Formula	C9H13N5·HCl
Molecular Weight	227.70 g/mol
Synonyms	4-(2-Aminopyrimidin-4-yl)piperidine hydrochloride; 2-Pyrimidinamine, 4-(4-piperidinyl)-, hydrochloride (1:1); 4-(4-Piperidinyl)-2-pyrimidinamine hydrochloride; 4-(2-Amino-pyrimidin-4-yl)-piperidine hydrochloride; 4-(Piperidin-4-yl)pyrimidin-2-amine hydrochloride; N-(4-Piperidinyl)-2-pyrimidinamine hydrochloride; 950649-10-2
EINECS	Contact for details

Quality Control

Our Piperidin-4-Yl-Pyrimidin-2-Yl-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.