Description

tert-Butyl 3-(pyrimidin-2-yloxy)pyrrolidine-1-carboxylate is a high-value, protected pyrrolidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where the pyrrolidine and pyrimidine motifs are key pharmacophores.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the biological activity of pyrimidine and heterocyclic amine structures.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic and R&D Laboratories: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 3-(Pyrimidin-2-yloxy)pyrrolidine-1-carboxylate
CAS No.	950648-94-9
Molecular Formula	C13H19N3O3
Molecular Weight	265.31 g/mol
Synonyms	1-Boc-3-(pyrimidin-2-yloxy)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-(pyrimidin-2-yloxy)pyrrolidine; tert-Butyl 3-(2-pyrimidinyloxy)-1-pyrrolidinecarboxylate; 3-(Pyrimidin-2-yloxy)pyrrolidine-1-carboxylic acid tert-butyl ester; 950648-94-9; Boc-3-(2-pyrimidyloxy)pyrrolidine; Pyrrolidine, 3-(2-pyrimidinyloxy)-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.