Description

Damgo Tfa CAS NO 950492-85-0 is a high-purity, synthetic peptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for studying opioid receptor pharmacology and developing novel therapeutic agents. It is essential for researchers and manufacturers in the fields of neuroscience, medicinal chemistry, and peptide-based drug discovery who require reliable, high-quality materials for their work.

Application

• Pharmacological Research: As a key reference standard in studies investigating the structure-activity relationships (SAR) of opioid peptides and their interactions with mu-opioid receptors.
• Medicinal Chemistry: Used as a crucial synthetic intermediate in the development and optimization of novel analgesic compounds and peptide-based therapeutics.
• Biochemical Assay Development: Employed in the calibration and validation of analytical methods, including HPLC and mass spectrometry, for quantifying opioid peptides in biological matrices.
• Neuroscience Studies: Applied in vitro and in vivo research models to elucidate pain pathways, receptor signaling mechanisms, and the effects of peptide modifications on biological activity.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and regulatory compliance in the production of related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Damgo Tfa
CAS No.	950492-85-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DAMGO TFA Salt; [D-Ala2, N-MePhe4, Gly-ol]-Enkephalin Trifluoroacetate; Tyr-D-Ala-Gly-N-Me-Phe-Gly-ol Trifluoroacetate; H-Tyr-D-Ala-Gly-N-Me-Phe-Gly-ol TFA; Mu-opioid receptor agonist DAMGO TFA; ID-Ala2, N-MePhe4, Gly-ol5]-Enkephalin TFA; Opioid peptide DAMGO TFA salt
EINECS	Contact for details

Quality Control

Every batch of Damgo Tfa is manufactured and tested under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic analyses, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.