Description

Methyl 3-Acetyl-5-Chlorobenzoate is a high-purity, versatile benzoate ester derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable building blocks for heterocyclic synthesis and structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with benzodiazepine or other fused heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging the chlorobenzoyl moiety.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new reaction pathways.
• Ligand and Catalyst Preparation: Useful for synthesizing complex organic ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.

Basic Information

Product Name	Methyl 3-Acetyl-5-Chlorobenzoate
CAS No.	950225-58-8
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	3-Acetyl-5-chlorobenzoic acid methyl ester; Methyl 3-acetyl-5-chlorobenzoate; Benzoic acid, 3-acetyl-5-chloro-, methyl ester; 5-Chloro-3-acetylbenzoic acid methyl ester; 3-Acetyl-5-chloro-benzoic acid methyl ester; Methyl 5-chloro-3-acetylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Acetyl-5-Chlorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.