Description

(S)-7-Phenyl-2-(Pyrrolidin-2-Yl)Thiazolo-[5,4-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily sought after by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery programs for central nervous system (CNS) disorders, oncology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel, potent drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities (NCEs).
• Biochemical Tool Compound: Employed in vitro and in vivo as a selective probe to study specific biological pathways and protein functions.
• Preclinical Development: Supplied in development quantities for formulation studies, pharmacokinetic (PK) profiling, and toxicology assessments.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	(S)-7-Phenyl-2-(Pyrrolidin-2-Yl)Thiazolo-[5,4-D]Pyrimidine Hydrochloride
CAS No.	950192-41-3
Molecular Formula	C17H16N4S • HCl
Molecular Weight	344.86 g/mol (Free base: 308.40 g/mol)
Synonyms	(S)-7-Phenyl-2-(2-pyrrolidinyl)thiazolo[5,4-d]pyrimidine hydrochloride; Thiazolo[5,4-d]pyrimidine, 7-phenyl-2-(2-pyrrolidinyl)-, hydrochloride, (S)-; (2S)-7-Phenyl-2-(pyrrolidin-2-yl)[1,3]thiazolo[5,4-d]pyrimidine hydrochloride; (S)-7-Phenyl-2-(2-pyrrolidinyl)-[1,3]thiazolo[5,4-d]pyrimidine HCl; CAS 950192-41-3
EINECS	Contact for details

Quality Control

Every batch of (S)-7-Phenyl-2-(Pyrrolidin-2-Yl)Thiazolo-[5,4-D]Pyrimidine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the rigorous standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting critical parameters such as assay (HPLC), chiral purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.