Description

L-Glutamic Acid, n-[[[(1S)-1-Carboxy-5-[[(4-Iodophenyl)Methyl]Amino]Pentyl]Amino]Carbonyl]- is a specialized, high-purity derivative of glutamic acid, engineered for advanced research and development applications. This compound is valued for its role as a key synthetic intermediate and building block in the creation of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on medicinal chemistry and peptide-based drug discovery.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors or receptor modulators.
• Peptide Mimetic Development: Used in the design and synthesis of peptidomimetics and constrained peptides due to its modified glutamic acid backbone and aromatic iodophenyl group.
• Bioconjugation and Probe Synthesis: Acts as a versatile linker or functional handle for creating fluorescent probes, affinity labels, or targeted conjugates for biochemical assays.
• Medicinal Chemistry Libraries: Incorporated into compound libraries for high-throughput screening to identify new leads with specific biological activity.
• Academic & Institutional Research: Supports fundamental studies in organic synthesis, chemical biology, and structure-activity relationship (SAR) analysis.

Basic Information

Product Name	L-Glutamic Acid, n-[[[(1S)-1-Carboxy-5-[[(4-Iodophenyl)Methyl]Amino]Pentyl]Amino]Carbonyl]-
CAS No.	949575-20-6
Molecular Formula	C19H26IN3O6
Molecular Weight	519.33 g/mol
Synonyms	N-[(S)-5-[[(4-Iodobenzyl)amino]-1-carboxypentyl]carbamoyl]-L-glutamic acid; (2S)-2-[[(2S)-5-[[(4-Iodophenyl)methyl]amino]-1-hydroxy-1-oxopentan-2-yl]carbamoylamino]pentanedioic acid; L-Glu-urea-iodobenzyl derivative; Glutamic acid derivative CAS 949575-20-6; Research compound 949575-20-6; Advanced pharmaceutical intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.