Description

(E)-Ethyl 3-(5-Fluoro-2-Hydroxyphenyl)Acrylate is a high-purity, fluorinated phenolic acrylate ester building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a phenolic hydroxyl group, an acrylate moiety, and a fluorine substituent, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties like UV resistance or specific adhesion.
• Liquid Crystal & OLED Materials: Acts as a fluorinated intermediate in the synthesis of advanced electronic materials for displays and lighting.
• Chemical Biology Probe Development: Utilized to create fluorescent or photoaffinity labels for studying biological processes and protein interactions.
• Fine Chemical Production: Employed in multi-step synthetic routes to produce complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(E)-Ethyl 3-(5-Fluoro-2-Hydroxyphenyl)Acrylate
CAS No.	949449-09-6
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl (E)-3-(5-Fluoro-2-hydroxyphenyl)acrylate; (E)-Ethyl 3-(5-Fluoro-2-hydroxyphenyl)propenoate; 5-Fluoro-2-hydroxycinnamic acid ethyl ester; Ethyl 5-fluoro-2-hydroxycinnamate; (2E)-3-(5-Fluoro-2-hydroxyphenyl)acrylic acid ethyl ester; Ethyl (E)-3-(5-fluoro-2-hydroxyphenyl)-2-propenoate; 949449-09-6; Acrylic acid, 3-(5-fluoro-2-hydroxyphenyl)-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(5-Fluoro-2-Hydroxyphenyl)Acrylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications in cGMP environments and research requiring the highest material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect this light-sensitive compound from degradation and to maintain its specified purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.