Description

p-Scn-Bn-Pcta is a bifunctional chelator and linker molecule, widely recognized in the field of radiopharmaceutical chemistry. Its core value lies in enabling the stable conjugation of radioactive isotopes, such as Gallium-68 or Lutetium-177, to targeting vectors like peptides and antibodies for diagnostic and therapeutic applications. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing next-generation targeted radionuclide therapies (TRT) and positron emission tomography (PET) imaging agents.

Application

• Radiopharmaceutical Precursor: A key intermediate for synthesizing PSMA-targeting and other theranostic agents.
• PET Imaging Probe Development: Used to create chelator-peptide conjugates for diagnostic imaging with isotopes like Gallium-68.
• Targeted Radionuclide Therapy (TRT): Facilitates the construction of therapeutic radiopharmaceuticals using β-emitters like Lutetium-177.
• Bifunctional Chelator (BFC) Research: Serves as a model compound in studying conjugation chemistry and chelate stability.
• Antibody-Drug Conjugate (ADC) Platforms: Explored for attaching payloads in advanced drug delivery systems.
• Molecular Imaging Agent Synthesis: Critical for labeling biomolecules with metallic radionuclides for non-invasive imaging.

Basic Information

Product Name	p-Scn-Bn-Pcta
CAS No.	949147-44-8
Molecular Formula	C₂₆H₃₄N₆O₇S
Molecular Weight	574.65 g/mol
Synonyms	2,2',2''-(1,4,7-Triazacyclononane-1,4,7-triyl)triacetic acid, 1-(4-Isothiocyanatobenzyl) derivative; p-SCN-Bn-PCTA; PCTA-(p-SCN-Bn); SCN-Bn-PCTA; 1-(4-Isothiocyanatobenzyl)-1,4,7-triazacyclononane-4,7-diacetic acid; Bifunctional Chelator PCTA; NOTA derivative p-SCN-Bn
EINECS	Contact for details

Quality Control

Our p-Scn-Bn-Pcta is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and pre-clinical development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers in pharmaceutical and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤2.0%
Heavy Metals	<10 ppm
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.