Description

Coccidioidin is a sterile, standardized antigenic preparation derived from the mycelial phase of the fungus *Coccidioides immitis*. This product is essential for the diagnosis of coccidioidomycosis (Valley Fever) through delayed-type hypersensitivity skin testing. It is a critical diagnostic reagent for clinical laboratories, public health organizations, and research institutions focused on fungal diseases and immunology.

Application

• Clinical Diagnostics: Primary use in the coccidioidin skin test (Mitsuda-type reaction) to detect exposure to or infection with *Coccidioides immitis*.
• Epidemiological Studies: Screening populations in endemic regions to determine the prevalence of coccidioidomycosis infection.
• Immunological Research: Used as a specific antigen to study cell-mediated immune responses, T-cell reactivity, and host-pathogen interactions related to *Coccidioides*.
• Veterinary Medicine: Potential application for diagnosing coccidioidomycosis in animals, particularly in endemic areas.
• Reference Standard: Serves as a quality control and standardization reference for in-house laboratory test preparations.
• Vaccine Research: Investigational use in the development and evaluation of potential vaccines against coccidioidomycosis.

Basic Information

Product Name	Coccidioidin
CAS No.	12622-73-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Coccidioidin Antigen; Coccidioides immitis Antigen; Coccidioidomycosis Skin Test Antigen; Spherulin (related preparation); Valley Fever Antigen; Coccidioides Antigen; Coccidioidin USP; Coccidioidin Diagnostic Antigen
EINECS	Contact for details

Quality Control

Our Coccidioidin is manufactured under stringent conditions to ensure sterility, specificity, and consistent potency. Each lot undergoes comprehensive testing including sterility, safety (abnormal toxicity), and potency/standardization against a reference preparation. We adhere to relevant guidelines for biological antigens. A Certificate of Analysis (COA) detailing all release specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Do not freeze. Keep the product in its original packaging until use.

Specification

Item	Specification
Description	Clear to slightly opalescent liquid
Identification (Immunodiffusion)	Positive reaction with reference antisera
Potency (Skin Test)	Standardized against reference lot
Sterility Test	Sterile
Safety Test (Abnormal Toxicity)	Passes test
pH	6.5 - 7.5
Protein Content	Specified range per lot
Preservative	May contain Phenol (≤0.5%)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.