Description

Protein 61, Varicella-Zoster Virus is a highly purified viral protein antigen derived from the Varicella-Zoster Virus (VZV), the causative agent of chickenpox and shingles. This critical reagent is essential for the research, development, and quality control of diagnostic assays and vaccine formulations targeting VZV. It serves as a fundamental component for biopharmaceutical companies, academic research institutions, and diagnostic manufacturers focused on virology and immunology.

Application

• Diagnostic Assay Development: Used as a key antigen in the production of ELISA kits, immunoblot assays, and other serological tests for detecting VZV-specific antibodies.
• Vaccine Research & Development: Serves as a reference standard and immunogen in the development and potency testing of varicella and shingles vaccines.
• Immunological Studies: Employed in basic research to study host immune response, viral pathogenesis, and antigen-antibody interactions related to VZV.
• Quality Control (QC) & Lot Release Testing: Acts as a critical standard in QC protocols for the validation and batch consistency testing of vaccine products and diagnostic reagents.
• Antibody Production & Purification: Utilized for the immunization of animals to generate polyclonal or monoclonal antibodies specific to VZV.
• Clinical Trial Support: Provides a standardized antigen for assessing immunogenicity in clinical trials for new therapeutic or prophylactic interventions.

Basic Information

Product Name	Protein 61, Varicella-Zoster Virus
CAS No.	106121-63-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VZV Protein 61; Varicella-Zoster Virus Glycoprotein; VZV gp61; Herpesvirus 3 Glycoprotein; HHV-3 Protein; Varicella-Zoster Virus Antigen; Chickenpox Virus Protein; VZV Envelope Glycoprotein
EINECS	Contact for details

Quality Control

Our Protein 61, Varicella-Zoster Virus is produced and tested under stringent quality management systems. Each lot undergoes rigorous analytical testing to ensure identity, purity, potency, and consistency, meeting the exacting standards required for research and bioprocessing applications. Certificates of Analysis (COA) detailing purity (by HPLC/SDS-PAGE), protein concentration, endotoxin levels, and functional activity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot as necessary to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE/Western Blot)	Consistent with VZV Protein 61
Purity (HPLC/SDS-PAGE)	≥ 90%
Protein Content	Determined by UV absorbance or BCA assay
Endotoxin	< 1.0 EU/µg
Biological Activity	Confirmed by ELISA or similar immunoassay
Sterility (if applicable)	Sterile filtered or tested

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.