Description

6-Hydroxy-3,4-Dihydroquinazolin-2(1H)-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to synthesize potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel quinazolinone-based drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Organic Synthesis Reference Standard: Serves as a pure standard for analytical method development and validation in QC laboratories.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	6-Hydroxy-3,4-Dihydroquinazolin-2(1H)-One
CAS No.	948552-89-4
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	6-Hydroxy-1,2,3,4-tetrahydroquinazolin-2-one; 6-Hydroxy-3,4-dihydro-2(1H)-quinazolinone; 2H-Quinazolin-2-one, 3,4-dihydro-6-hydroxy-1,4-dihydro-6-hydroxyquinazolin-2(1H)-one; 6-Hydroxydihydroquinazolinone; 6-Hydroxy-1,2,3,4-tetrahydro-2-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-3,4-Dihydroquinazolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.