Description

(E)-3-(4-Fluorobenzylidene)-2,3-Dihydrochromen-4-One CAS NO 948307-89-9 is a high-purity, synthetic organic compound belonging to the chromenone class, characterized by its distinct fluorinated benzylidene moiety. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block for research and development in medicinal chemistry. It is primarily utilized by R&D laboratories and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for therapeutic areas targeting inflammation, CNS disorders, and oncology.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of new-generation pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Organic Synthesis Building Block: Employed in complex organic transformations, including cyclization and cross-coupling reactions, to create diverse heterocyclic compounds.
• Material Science Research: Investigated as a potential monomer or additive for developing specialty polymers and organic electronic materials due to its conjugated system.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	(E)-3-(4-Fluorobenzylidene)-2,3-Dihydrochromen-4-One
CAS No.	948307-89-9
Molecular Formula	C16H11FO2
Molecular Weight	254.26 g/mol
Synonyms	3-[(E)-4-Fluorobenzylidene]chroman-4-one; 4H-1-Benzopyran-4-one, 3-[(E)-4-fluorobenzylidene]-2,3-dihydro-; (E)-3-(4-Fluorobenzylidene)chroman-4-one; 3-(4-Fluorobenzylidene)-4-chromanone; 948307-89-9; Fluorobenzylidene chromenone; 4-Fluorobenzylidene dihydrochromenone
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Fluorobenzylidene)-2,3-Dihydrochromen-4-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.