Description

2-Amino-5-(3-Chlorophenyl)Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a chlorophenyl substituent, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides that require specific pyrimidine-based scaffolds.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing more complex heterocyclic compounds in academic and industrial R&D laboratories.
• Bioconjugation & Probe Development: The amino group allows for coupling reactions, useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	2-Amino-5-(3-Chlorophenyl)Pyrimidine
CAS No.	947592-43-0
Molecular Formula	C10H8ClN3
Molecular Weight	205.64 g/mol
Synonyms	5-(3-Chlorophenyl)pyrimidin-2-amine; 2-Pyrimidinamine, 5-(3-chlorophenyl)-; 3-Chloro-5-(2-aminopyrimidin-5-yl)benzene; 2-Amino-5-(m-chlorophenyl)pyrimidine; 5-(3-Chlorophenyl)-2-pyrimidinamine; 2-Amino-5-(3-chlorophenyl)pyrimidine; (3-Chlorophenyl)-5-pyrimidin-2-yl-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(3-Chlorophenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.