Description

2-Bromo-5-Fluoropyrimidine is a high-purity fluorinated pyrimidine building block essential for modern synthetic chemistry. This compound is a critical intermediate in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with improved efficacy.
• Material Science Research: Serves as a precursor for creating functionalized polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleoside Analog Development: Employed in the modification of nucleosides for potential therapeutic applications.
• Chemical Biology Probes: Used to create labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	2-Bromo-5-Fluoropyrimidine
CAS No.	947533-45-1
Molecular Formula	C4H2BrFN2
Molecular Weight	176.97 g/mol
Synonyms	5-Fluoro-2-bromopyrimidine; 2-Bromo-5-fluoropyrimidine; 5-Fluoro-2-pyrimidinyl bromide; Pyrimidine, 2-bromo-5-fluoro-; 947533-45-1
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.