Description

1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-[[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methyl]- is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring both pyrrole and pyrimidine rings with protected amine functionality, makes it a critical intermediate for constructing novel pharmacologically active compounds. This high-purity chemical is essential for research and development teams in the pharmaceutical and biotechnology sectors, particularly those focused on kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Biochemical Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic scaffolds in academic and industrial laboratories.
• Agrochemical Development: Potential intermediate in the research and synthesis of new active ingredients for crop protection.
• Material Science: Exploration of functional organic materials and dyes due to its conjugated pyrrole-pyrimidine core.

Basic Information

Product Name	1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-[[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methyl]-
CAS No.	947327-44-8
Molecular Formula	C16H19N5O4
Molecular Weight	345.36 g/mol
Synonyms	5-(2-Aminopyrimidin-4-yl)-2-[[(tert-butoxycarbonyl)amino]methyl]-1H-pyrrole-3-carboxylic acid; 2-[(tert-Butoxycarbonylamino)methyl]-5-(2-aminopyrimidin-4-yl)-1H-pyrrole-3-carboxylic acid; Boc-protected pyrrole-pyrimidine carboxylic acid; tert-Butyl N-[[5-(2-aminopyrimidin-4-yl)-3-carboxy-1H-pyrrol-2-yl]methyl]carbamate; CAS 947327-44-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.