Description

4-(3,4-Difluorophenoxy)-2-Methylaniline is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorophenoxy aniline structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas, where its precise molecular architecture enables key pharmacological activity. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the biological activity of the difluorophenoxy moiety.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed as a standard or reagent in organic synthesis for creating complex aromatic ether and amine derivatives.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	4-(3,4-Difluorophenoxy)-2-Methylaniline
CAS No.	946786-40-9
Molecular Formula	C13H11F2NO
Molecular Weight	235.23 g/mol
Synonyms	2-Methyl-4-(3,4-difluorophenoxy)aniline; 4-(3,4-Difluorophenoxy)-2-methylbenzenamine; 2-Methyl-4-(3,4-difluorophenoxy)benzenamine; Benzenamine, 4-(3,4-difluorophenoxy)-2-methyl-; 946786-40-9; 4-(3,4-Difluorophenoxy)-o-toluidine
EINECS	Contact for details

Quality Control

Our 4-(3,4-Difluorophenoxy)-2-Methylaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.