Description

4-(2,5-Dimethylphenoxy)-2-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring a trifluoromethyl group and a dimethylphenoxy substituent, making it a valuable fluorinated building block. This compound is significant for its role in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate this specific fluorinated aniline scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Intermediate: Acts as a building block for creating novel fluorinated dyes and pigments with unique color fastness and optical properties.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new reactions and creating compound libraries for high-throughput screening.

Basic Information

Product Name	4-(2,5-Dimethylphenoxy)-2-(Trifluoromethyl)Aniline
CAS No.	946784-57-2
Molecular Formula	C15H14F3NO
Molecular Weight	281.27 g/mol
Synonyms	2-(Trifluoromethyl)-4-(2,5-dimethylphenoxy)aniline; 4-(2,5-Dimethylphenoxy)-2-(trifluoromethyl)benzenamine; 2-(Trifluoromethyl)-4-(2,5-dimethylphenoxy)benzenamine; 4-(2,5-Dimethylphenoxy)-α,α,α-trifluoro-o-toluidine; 4-(2,5-Xylenoxy)-2-(trifluoromethyl)aniline; 2-Trifluoromethyl-4-(2,5-dimethylphenoxy)aniline; Benzenamine, 4-(2,5-dimethylphenoxy)-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-(2,5-Dimethylphenoxy)-2-(Trifluoromethyl)Aniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC), impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.