Description

2-(2-Ethoxyethoxy)-5-Fluoroaniline is a specialized aromatic amine derivative featuring both fluoro and ethoxyethoxy substituents. This compound is a high-value intermediate prized for its role in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for manufacturers and R&D teams developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional dyes who require consistent purity and reliable supply chains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies (LCDs).
• Functional Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments where the aniline and fluoro groups contribute to color fastness and unique optical properties.
• Organic Electronic Materials: Investigated as a component in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex aromatic amines.

Basic Information

Product Name	2-(2-Ethoxyethoxy)-5-Fluoroaniline
CAS No.	946774-73-8
Molecular Formula	C10H14FNO2
Molecular Weight	199.22 g/mol
Synonyms	5-Fluoro-2-(2-ethoxyethoxy)aniline; 2-(2-Ethoxyethoxy)-5-fluoro-benzenamine; 1-Ethoxy-2-[(2-fluoro-5-aminophenoxy)ethoxy]ethane; 5-Fluoro-2-(β-ethoxyethoxy)aniline; Benzenamine, 2-(2-ethoxyethoxy)-5-fluoro-; 2-Amino-4-fluoro-1-(2-ethoxyethoxy)benzene
EINECS	Contact for details

Quality Control

Our 2-(2-Ethoxyethoxy)-5-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to amber liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.