Description

3-Fluoro-4-(Tetrahydro-2-Furanylmethoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique aniline derivative structure with a tetrahydrofuran methoxy substituent. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific fluorine and ether functionalities enable precise molecular modifications. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its fluorine moiety for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory testing.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-(Tetrahydro-2-Furanylmethoxy)Aniline
CAS No.	946742-26-3
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	3-Fluoro-4-[(tetrahydrofuran-2-yl)methoxy]aniline; 4-Amino-2-fluoro-1-[(tetrahydro-2-furanyl)methoxy]benzene; 3-Fluoro-4-(tetrahydrofuran-2-ylmethoxy)benzenamine; 946742-26-3; 3-Fluoro-4-(THF-2-ylmethoxy)aniline; FTHFMA; 2-Furanylmethoxy, tetrahydro-, 4-amino-3-fluoro- derivative
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Tetrahydro-2-Furanylmethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.