Description

2-(3,5-Dimethylphenoxy)-5-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring a trifluoromethyl group, making it a valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral medications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Industry: Acts as an intermediate for producing high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amine structures.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the properties and reactivities of fluorinated aromatic systems.

Basic Information

Item	Details
Product Name	2-(3,5-Dimethylphenoxy)-5-(Trifluoromethyl)Aniline
CAS No.	946715-48-6
Molecular Formula	C15H14F3NO
Molecular Weight	281.27 g/mol
Synonyms	5-(Trifluoromethyl)-2-(3,5-dimethylphenoxy)aniline; 2-(3,5-Dimethylphenoxy)-5-(trifluoromethyl)benzenamine; 2-Amino-4'-(trifluoromethyl)-3,5-dimethyl diphenyl ether; 5-Trifluoromethyl-2-(3,5-dimethylphenoxy)phenylamine; Benzenamine, 2-(3,5-dimethylphenoxy)-5-(trifluoromethyl)-; [946715-48-6]
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Dimethylphenoxy)-5-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity profiles, to ensure consistent quality and traceability for your critical R&D and production processes. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.