Description

(2'-Fluoro[1,1'-Biphenyl]-2-Yl)Methanamine is a high-purity, fluorinated biphenyl amine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a biphenyl core with a strategically placed fluorine atom and a primary amine functional group, enabling precise structural modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in developing new-generation herbicides and fungicides where the fluorinated biphenyl moiety enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to its amine handle for conjugation.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and CDMOs requiring reliable, high-quality advanced intermediates.

Basic Information

Product Name	(2'-Fluoro[1,1'-Biphenyl]-2-Yl)Methanamine
CAS No.	946714-14-3
Molecular Formula	C13H12FN
Molecular Weight	201.24 g/mol
Synonyms	2'-(Aminomethyl)-2-fluorobiphenyl; [1,1'-Biphenyl]-2-methanamine, 2'-fluoro-; 2-(Aminomethyl)-2'-fluorobiphenyl; (2-Fluorobiphenyl-2-yl)methanamine; 2'-Fluoro-2-biphenylmethanamine; 2-(Aminomethyl)-2'-fluoro-1,1'-biphenyl; 2'-Fluorobiphenyl-2-ylmethylamine
EINECS	Contact for details

Quality Control

Every batch of (2'-Fluoro[1,1'-Biphenyl]-2-Yl)Methanamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements of advanced R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.