Description

4-(2-Fluorophenoxy)-2-Methylaniline is a specialized aromatic amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both a fluorophenoxy group and a methyl-substituted aniline, making it a versatile intermediate for creating complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, dyes, or liquid crystals.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	4-(2-Fluorophenoxy)-2-Methylaniline
CAS No.	946699-47-4
Molecular Formula	C13H12FNO
Molecular Weight	217.24 g/mol
Synonyms	2-Methyl-4-(2-fluorophenoxy)aniline; 2-Methyl-4-(o-fluorophenoxy)aniline; 4-(2-Fluorophenoxy)-2-methylbenzenamine; 2-Fluoro-4-(2-methyl-4-aminophenoxy)benzene (rearranged); Benzenamine, 4-(2-fluorophenoxy)-2-methyl-; 2-Methyl-4-(2-fluorophenoxy)phenylamine
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Fluorophenoxy)-2-Methylaniline is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality, it should be stored separately from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.