Description

(2-Fluoro-3-Nitrophenyl)Methanol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a nitro group ortho to a hydroxymethyl function, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Cross-Coupling Reactions: The functional groups present make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Dye & Pigment Chemistry: Utilized in the development of specialized nitro- and fluoro-containing dyes with unique chromatic and fastness properties.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry and for custom synthesis projects.

Basic Information

Item	Detail
Product Name	(2-Fluoro-3-Nitrophenyl)Methanol
CAS No.	946126-95-0
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	2-Fluoro-3-nitrobenzenemethanol; (2-Fluoro-3-nitrophenyl)carbinol; 1-(2-Fluoro-3-nitrophenyl)methanol; 2-Fluoro-3-nitrobenzyl alcohol; α-Hydroxymethyl-2-fluoro-3-nitrobenzene; Benzenemethanol, 2-fluoro-3-nitro-; 3-Nitro-2-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our production of (2-Fluoro-3-Nitrophenyl)Methanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.