Description

Imidazo[4,5:4,5]Cyclopenta[1,2-D]Pyrimidin-7(3H)-One, 5-Amino-6,8-Dihydro- is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant commercial interest as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily utilized by R&D laboratories, custom synthesis providers, and pharmaceutical manufacturers engaged in developing next-generation small molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the development of novel chemotherapeutic agents and targeted cancer therapies.
• Antiviral Drug Development: Employed as a scaffold for creating compounds with potential activity against various viruses.
• Biochemical Research: Acts as a specialized reagent or ligand in proteomics and enzyme inhibition studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and reaction pathways in medicinal chemistry.

Basic Information

Product Name	Imidazo[4,5:4,5]Cyclopenta[1,2-D]Pyrimidin-7(3H)-One, 5-Amino-6,8-Dihydro-
CAS No.	946087-66-7
Molecular Formula	C8H7N5O
Molecular Weight	189.17 g/mol
Synonyms	5-Amino-6,8-dihydroimidazo[4,5:4,5]cyclopenta[1,2-d]pyrimidin-7(3H)-one; 5-Amino-3,6,8,8a-tetrahydro-7H-imidazo[4,5:4,5]cyclopenta[1,2-d]pyrimidin-7-one; 5-Amino-6,8-dihydro-3H-imidazo[4,5:4,5]cyclopenta[1,2-d]pyrimidin-7-one; CAS 946087-66-7; Advanced Heterocyclic Building Block
EINECS	Contact for details

Quality Control

Our production of Imidazo[4,5:4,5]Cyclopenta[1,2-D]Pyrimidin-7(3H)-One, 5-Amino-6,8-Dihydro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All materials are characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.