Description

1-(3,4-Difluorophenyl)-2,2,2-Trifluoroethanol is a high-value fluorinated aromatic alcohol building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique fluorine substitution pattern imparts desirable metabolic stability and lipophilicity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides and fungicides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Serves as a precursor for materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: A versatile reagent in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Custom Synthesis: Employed in contract manufacturing and custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	1-(3,4-Difluorophenyl)-2,2,2-Trifluoroethanol
CAS No.	945978-37-0
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	2,2,2-Trifluoro-1-(3,4-difluorophenyl)ethanol; (3,4-Difluorophenyl)(trifluoromethyl)methanol; 1-(3,4-Difluorophenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-3,4-difluorobenzyl alcohol; 3,4-Difluoro-α-(trifluoromethyl)benzyl Alcohol; 945978-37-0; FC-1133 (potential research code)
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluorophenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity chemical intermediates for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.