Description

6-Chloro-n-(4-Fluorobenzyl)Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyrimidine core structure. This compound is critical for medicinal chemistry research and the synthesis of targeted therapeutic agents, offering a versatile building block for drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Agrochemical Research: Potential intermediate for developing new crop protection agents and pesticides due to its heterocyclic structure.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	6-Chloro-n-(4-Fluorobenzyl)Pyrimidin-4-Amine
CAS No.	945896-79-7
Molecular Formula	C11H9ClFN3
Molecular Weight	237.66 g/mol
Synonyms	6-Chloro-N-[(4-fluorophenyl)methyl]pyrimidin-4-amine; 4-Amino-6-chloro-N-(4-fluorobenzyl)pyrimidine; 6-Chloro-N-(4-fluorobenzyl)-4-pyrimidinamine; 945896-79-7; 6-Chloro-N-(4-fluorobenzyl)pyrimidin-4-amine; 4-Pyrimidinamine, 6-chloro-N-[(4-fluorophenyl)methyl]-; N-(4-Fluorobenzyl)-6-chloropyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-n-(4-Fluorobenzyl)Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.