Description

n-(tert-Butyl)-6-Chloropyrimidin-4-Amine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific amine and halogen functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile building block for constructing heterocyclic libraries in medicinal and combinatorial chemistry.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	n-(tert-Butyl)-6-Chloropyrimidin-4-Amine
CAS No.	945896-38-8
Molecular Formula	C8H12ClN3
Molecular Weight	185.65 g/mol
Synonyms	6-Chloro-N-(tert-butyl)pyrimidin-4-amine; 4-Amino-6-chloro-N-tert-butylpyrimidine; 6-Chloro-4-[(1,1-dimethylethyl)amino]pyrimidine; tert-Butyl-(6-chloropyrimidin-4-yl)amine; N-(tert-Butyl)-6-chloro-4-pyrimidinamine; 6-Chloro-N-(1,1-dimethylethyl)-4-pyrimidinamine; 945896-38-8; 6-Chloro-4-(tert-butylamino)pyrimidine
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-6-Chloropyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.