Description

(2-Chloro-Pyrimidin-4-Yl)-Cyclopropyl-Amine is a high-purity, functionalized pyrimidine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors focused on creating new small-molecule therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Employed to create molecular tools for studying biological pathways and protein functions.
• Material Science: Acts as a building block for functionalized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis and scale-up projects.

Basic Information

Product Name	(2-Chloro-Pyrimidin-4-Yl)-Cyclopropyl-Amine
CAS No.	945895-52-3
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-4-(cyclopropylamino)pyrimidine; Cyclopropyl-(2-chloropyrimidin-4-yl)amine; 4-Amino-2-chloro-N-cyclopropylpyrimidine; 2-Chloro-N-cyclopropylpyrimidin-4-amine; (2-Chloro-4-pyrimidinyl)cyclopropylamine; 945895-52-3; 2-Chloro-4-(cyclopropylamino)pyrimidine
EINECS	Contact for details

Quality Control

Our (2-Chloro-Pyrimidin-4-Yl)-Cyclopropyl-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.