Description

2-Chloro-n-Piperidin-4-Ylpyrimidin-4-Amine CAS NO 945895-43-2 is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with a chloro group and a piperidin-4-ylamine moiety. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing novel small-molecule libraries for biological screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Its structure is conducive to the development of compounds that modulate kinase activity, relevant in oncology and inflammatory diseases.
• Chemical Biology Probes: Used to create tool compounds for investigating specific biological targets and pathways in academic and industrial research settings.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects requiring complex heterocycles.

Basic Information

Product Name	2-Chloro-n-Piperidin-4-Ylpyrimidin-4-Amine
CAS No.	945895-43-2
Molecular Formula	C9H13ClN4
Molecular Weight	212.68 g/mol
Synonyms	2-Chloro-N-(piperidin-4-yl)pyrimidin-4-amine; 4-Amino-2-chloro-N-piperidin-4-ylpyrimidine; 2-Chloro-4-(piperidin-4-ylamino)pyrimidine; 945895-43-2; 2-Chloro-N-(4-piperidinyl)-4-pyrimidinamine; 4-Pyrimidinamine, 2-chloro-N-4-piperidinyl-
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.