Description

4-(2-(4-Morpholinophenylamino)Pyrimidin-4-Yl)Benzoic Acid is a sophisticated organic compound featuring a benzoic acid core linked to a substituted pyrimidine-morpholine pharmacophore. This molecular architecture makes it a valuable intermediate in advanced pharmaceutical research and development, particularly for targeting specific kinase pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a core scaffold or precursor for developing high-affinity ligands and probes in molecular biology studies.
• Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes for candidate drugs during preclinical and clinical development.
• Academic Research: Employed in universities and research institutes for exploring new chemical entities and structure-activity relationships (SAR).
• Custom Synthesis: Basis for producing tailored derivatives and analogs for specialized client projects in drug discovery.

Basic Information

Product Name	4-(2-(4-Morpholinophenylamino)Pyrimidin-4-Yl)Benzoic Acid
CAS No.	945749-71-3
Molecular Formula	C21H20N4O3
Molecular Weight	376.41 g/mol
Synonyms	4-[2-[(4-Morpholinophenyl)amino]pyrimidin-4-yl]benzoic acid; Benzoic acid, 4-[2-[(4-morpholinophenyl)amino]-4-pyrimidinyl]-; 4-(2-((4-Morpholinophenyl)amino)pyrimidin-4-yl)benzoic acid; 4-(2-(4-Morpholinoanilino)pyrimidin-4-yl)benzoic acid; 945749-71-3; UNII-8Q6K5P8F2F; 8Q6K5P8F2F
EINECS	Contact for details

Quality Control

Our production of 4-(2-(4-Morpholinophenylamino)Pyrimidin-4-Yl)Benzoic Acid adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.