Description

Propanedioic Acid, 2-(Acetylamino)-2-(1,2,3,4-Tetrahydro-6-Octyl-2-Naphthalenyl)-, 1,3-Diethyl Ester is a high-purity, synthetically derived organic compound featuring a complex molecular architecture combining a tetralin core with a functionalized malonate ester. This compound matters as a critical advanced intermediate in the synthesis of complex pharmacologically active molecules, offering precise stereochemistry and functional group compatibility for demanding chemical transformations. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex, modifiable scaffold.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of specialized ligands, catalysts, or other high-value organic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Details
Product Name	Propanedioic Acid, 2-(Acetylamino)-2-(1,2,3,4-Tetrahydro-6-Octyl-2-Naphthalenyl)-, 1,3-Diethyl Ester
CAS No.	945632-81-5
Molecular Formula	C27H39NO5
Molecular Weight	457.61 g/mol
Synonyms	2-Acetamido-2-(6-octyl-1,2,3,4-tetrahydro-2-naphthyl)malonic Acid Diethyl Ester; Diethyl 2-Acetamido-2-(6-octyl-1,2,3,4-tetrahydro-2-naphthyl)malonate; 2-(Acetylamino)-2-(6-octyl-1,2,3,4-tetrahydro-2-naphthalenyl)-1,3-diethyl Propanedioate; Malonic acid, 2-(acetylamino)-2-(1,2,3,4-tetrahydro-6-octyl-2-naphthalenyl)-, diethyl ester; CAS 945632-81-5
EINECS	Contact for details

Quality Control

Our Propanedioic Acid, 2-(Acetylamino)-2-(1,2,3,4-Tetrahydro-6-Octyl-2-Naphthalenyl)-, 1,3-Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support development and cGMP-grade requirements, with documentation tailored to your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.