Description

5-Bromo-2-Fluoro-4-Methylaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile handle for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for synthesizing fluorinated aromatic cores essential in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Dye Chemistry: Employed in the synthesis of specialty polymers, dyes, and pigments, where it modifies color fastness, solubility, and thermal properties.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Methylaniline
CAS No.	945244-29-1
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	4-Amino-2-bromo-5-fluorotoluene; 2-Bromo-5-fluoro-4-methylaniline; 4-Methyl-2-fluoro-5-bromoaniline; Benzenamine, 5-bromo-2-fluoro-4-methyl-; 5-Bromo-2-fluoro-p-toluidine; 2-Fluoro-5-bromo-4-methylaniline; 5-Bromo-2-fluoro-4-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.