Description

Diethyl 2-(2-Bromo-4-Nitrophenyl)-2-Methylmalonate is a high-purity, synthetically valuable organic intermediate. This compound is crucial for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those containing substituted aromatic and malonate ester motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromo and nitro groups for further functionalization.
• Organic Synthesis Building Block: Serves as a critical starting material in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to the presence of the bromine atom.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where specific aromatic and ester functionalities are required.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies and the construction of complex, polyfunctional organic compounds for various applications.

Basic Information

Item	Details
Product Name	Diethyl 2-(2-Bromo-4-Nitrophenyl)-2-Methylmalonate
CAS No.	945244-26-8
Molecular Formula	C₁₄H₁₆BrNO₆
Molecular Weight	374.19 g/mol
Synonyms	Diethyl (2-bromo-4-nitrophenyl)(methyl)propanedioate; 2-Bromo-4-nitrophenylmethylmalonic Acid Diethyl Ester; Propanedioic acid, 2-(2-bromo-4-nitrophenyl)-2-methyl-, 1,3-diethyl ester; Diethyl 2-methyl-2-(2-bromo-4-nitrophenyl)malonate; Ethyl 2-(2-bromo-4-nitrophenyl)-2-methylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl 2-(2-Bromo-4-Nitrophenyl)-2-Methylmalonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.