Description

Macimorelin Acetate is a synthetic growth hormone secretagogue receptor agonist, specifically formulated as the acetate salt for enhanced stability and pharmaceutical utility. This compound is of critical importance in clinical diagnostics and endocrinology research for its role in stimulating growth hormone release. It is primarily required by pharmaceutical manufacturers, clinical research organizations (CROs), and diagnostic kit producers for the development and production of growth hormone deficiency (GHD) diagnostic tests.

Application

• Diagnostic Pharmaceutical Ingredient: Key active component in diagnostic kits for assessing growth hormone deficiency (GHD) in adults and children.
• Clinical Research: Used in endocrinology studies to investigate the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and related metabolic pathways.
• Drug Development: Serves as a reference standard and a tool compound in the research and development of novel growth hormone secretagogues.
• Biochemical Research: Utilized in in vitro assays to study the function and signaling of the ghrelin/growth hormone secretagogue receptor (GHSR).
• GMP Manufacturing: Supplied as a high-purity active pharmaceutical ingredient (API) for the production of finished diagnostic products under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Macimorelin Acetate
CAS No.	945212-59-9
Molecular Formula	C28H40ClN5O3 • C2H4O2
Molecular Weight	602.13 g/mol
Synonyms	AEZS-130; EP-01572; GHRP-2 D-Lys3; Growth Hormone-Releasing Peptide-2 D-Lysine3; Macimorelin acetate salt; (D-Lys3)-GHRP-2 acetate; ARP 1006; UNII-9Q0I0U3V0K
EINECS	Contact for details

Quality Control

Our Macimorelin Acetate is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality is assured through a comprehensive battery of analytical tests including HPLC for purity, chiral chromatography for stereochemical identity, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, ensuring traceability and compliance with relevant pharmacopeial guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F), or as indicated on the label. The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm
Single Unknown Impurity	≤0.5%
Total Impurities	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.