Description

3-Methoxy-4-(Trifluoromethyl)Benzaldehyde is a high-purity aromatic aldehyde building block distinguished by its methoxy and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transporting layers in display and lighting technologies.
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments with tailored optical properties.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Ligand & Catalyst Development: Used to synthesize novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-Methoxy-4-(Trifluoromethyl)Benzaldehyde
CAS No.	945003-38-3
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	4-(Trifluoromethyl)-3-methoxybenzaldehyde; 3-Methoxy-4-trifluoromethylbenzaldehyde; 3-Methoxy-α,α,α-trifluoro-p-tolualdehyde; 4-Formyl-2-methoxybenzotrifluoride; 2-Methoxy-α,α,α-trifluoro-4-formyltoluene; p-(Trifluoromethyl)-m-anisaldehyde; 3-Methoxy-4-(trifluoromethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.