Description

(5-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine is a high-purity pyrimidine derivative featuring a reactive primary amine group and a stable trifluoromethyl substituent. This compound is a critical building block in modern pharmaceutical and agrochemical research, valued for its ability to impart metabolic stability and modulate physicochemical properties in target molecules. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of small-molecule drugs, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Active Ingredient Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Chemical Biology & Proteomics: Serves as a versatile linker or labeling reagent in the design of chemical probes and activity-based protein profiling (ABPP) studies.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials that require fluorinated aromatic systems.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to client-specific molecular scaffolds.

Basic Information

Product Name	(5-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine
CAS No.	944905-50-4
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	1-(5-(Trifluoromethyl)pyrimidin-2-yl)methanamine; 2-(Aminomethyl)-5-(trifluoromethyl)pyrimidine; (5-Trifluoromethyl-2-pyrimidinyl)methylamine; 5-(Trifluoromethyl)-2-pyrimidinemethanamine; 2-Aminomethyl-5-trifluoromethylpyrimidine; 5-(Trifluoromethyl)pyrimidine-2-methanamine
EINECS	Contact for details

Quality Control

Our (5-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.