Description

C-[2-(2,2,2-Trifluoro-Ethoxy)-Pyrimidin-5-Yl]-Methylamine is a high-value trifluoroethoxy-substituted pyrimidine derivative, a key building block in modern synthetic chemistry. This compound matters for its role as a critical intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique fluorine-containing moiety can significantly alter biological activity and metabolic stability. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this sophisticated heterocyclic scaffold into novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the pyrimidine core and fluorine atoms enhance efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Material Science Research: Potential precursor for the development of advanced organic electronic materials or liquid crystals due to its rigid, heteroaromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Item	Details
Product Name	C-[2-(2,2,2-Trifluoro-Ethoxy)-Pyrimidin-5-Yl]-Methylamine
CAS No.	944905-26-4
Molecular Formula	C7H8F3N3O
Molecular Weight	207.15 g/mol
Synonyms	5-(Aminomethyl)-2-(2,2,2-trifluoroethoxy)pyrimidine; (2-(2,2,2-Trifluoroethoxy)pyrimidin-5-yl)methanamine; 2-(2,2,2-Trifluoroethoxy)-5-pyrimidinemethanamine; 5-(Aminomethyl)-2-(trifluoroethoxy)pyrimidine; C-[2-(2,2,2-Trifluoroethoxy)pyrimidin-5-yl]methylamine; 944905-26-4; Trifluoroethoxy Pyrimidine Methylamine Derivative
EINECS	Contact for details

Quality Control

Our C-[2-(2-(2,2,2-Trifluoro-Ethoxy)-Pyrimidin-5-Yl]-Methylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to strong alkali and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.