Description

5-Chloro-2-Pyrrolidin-3-Ylpyrimidine is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex pyrimidine derivatives.
• Academic Research: Used in universities and research institutes for methodological development and exploring new chemical reactions.

Basic Information

Product Name	5-Chloro-2-Pyrrolidin-3-Ylpyrimidine
CAS No.	944903-08-6
Molecular Formula	C8H10ClN3
Molecular Weight	183.64 g/mol
Synonyms	5-Chloro-2-(3-pyrrolidinyl)pyrimidine; 2-(3-Pyrrolidinyl)-5-chloropyrimidine; 5-Chloro-2-pyrrolidin-3-yl-pyrimidine; 944903-08-6; 5-Chloro-2-(pyrrolidin-3-yl)pyrimidine; Pyrrolidin-3-yl, 5-chloro-2-pyrimidinyl derivative
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Pyrrolidin-3-Ylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity building blocks for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.