Description

2-Chloroquinazoline-4-Carbaldehyde is a versatile and high-value heterocyclic building block, primarily used as a key intermediate in advanced organic synthesis. Its reactive aldehyde and chlorinated quinazoline core make it indispensable for constructing complex molecular architectures. This compound is critical for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.
• Chemical Synthesis: Enables the introduction of the quinazoline scaffold and further functionalization via the aldehyde group for creating diverse chemical libraries.

Basic Information

Product Name	2-Chloroquinazoline-4-Carbaldehyde
CAS No.	944903-02-0
Molecular Formula	C9H5ClN2O
Molecular Weight	192.60 g/mol
Synonyms	4-Formyl-2-chloroquinazoline; 2-Chloro-4-quinazolinecarboxaldehyde; 2-Chloroquinazoline-4-carboxaldehyde; Quinazoline-4-carboxaldehyde, 2-chloro-; 2-Chloro-4-formylquinazoline; 2-Chlor-4-chinazolincarbaldehyd (German); Aldéhyde 2-chloro-4-quinazolinecarboxylique (French)
EINECS	Contact for details

Quality Control

Our 2-Chloroquinazoline-4-Carbaldehyde is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and GC-MS, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.