Description

5-Bromo-2-Chloromethylpyrimidine Hydrochloride is a high-purity, halogenated pyrimidine building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile precursor in medicinal chemistry and process development for creating diverse pyrimidine libraries.
• Material Science: Potential intermediate for the development of specialty polymers and organic electronic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5-Bromo-2-Chloromethylpyrimidine Hydrochloride
CAS No.	944903-00-8
Molecular Formula	C5H5BrCl2N2
Molecular Weight	256.92 g/mol
Synonyms	2-Chloromethyl-5-bromopyrimidine hydrochloride; 5-Bromo-2-(chloromethyl)pyrimidine hydrochloride; 5-Bromo-2-pyrimidinylmethyl chloride hydrochloride; Pyrimidine, 5-bromo-2-(chloromethyl)-, hydrochloride; 944903-00-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloromethylpyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.