Description

(4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine is a high-value trifluoromethylated pyrimidine derivative, a key building block in modern synthetic chemistry. Its core value lies in introducing the metabolically stable and lipophilic trifluoromethyl group into target molecules, significantly enhancing their biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to its distinct fluorine signature, useful in 19F-NMR studies and bio-conjugation strategies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine
CAS No.	944902-50-5
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	2-(Aminomethyl)-4-(trifluoromethyl)pyrimidine; 1-[4-(Trifluoromethyl)pyrimidin-2-yl]methanamine; 4-(Trifluoromethyl)-2-pyrimidinemethanamine; (4-Trifluoromethyl-pyrimidin-2-yl)-methylamine; 2-(Aminomethyl)-4-trifluoromethylpyrimidine; 4-(Trifluoromethyl)-2-(aminomethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our (4-(Trifluoromethyl)Pyrimidin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.