Description

2-(Aminomethyl)Pyrimidin-4-Ol is a versatile pyrimidine derivative featuring both amino and hydroxyl functional groups, making it a valuable building block in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals due to its bifunctional reactivity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Chelating Agent: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Bioconjugation and Linker Chemistry: The aminomethyl group enables its use in creating peptide mimetics, antibody-drug conjugates (ADCs), and other bioconjugates.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for developing enzyme inhibitors and molecular probes for biological research.

Basic Information

Product Name	2-(Aminomethyl)Pyrimidin-4-Ol
CAS No.	944902-47-0
Molecular Formula	C5H7N3O
Molecular Weight	125.13 g/mol
Synonyms	4-Pyrimidinol, 2-(aminomethyl)-; 2-(Aminomethyl)-4-pyrimidinol; 2-(Aminomethyl)pyrimidin-4(3H)-one; 4-Hydroxy-2-(aminomethyl)pyrimidine; (4-Hydroxypyrimidin-2-yl)methanamine; 2-(Aminomethyl)-4-hydroxypyrimidine; 2-(Aminomethyl)-4(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-(Aminomethyl)Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.