Description

1-(4-Chloropyrimidin-2-Yl)Methanamine is a high-purity organic building block featuring a chloropyrimidine core with an amine functional group. This compound is a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, crop protection, and fine chemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds in drug discovery.
• Material Science: Potential precursor for the synthesis of specialty polymers and ligands for catalysis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1-(4-Chloropyrimidin-2-Yl)Methanamine
CAS No.	944902-16-3
Molecular Formula	C5H5ClN3
Molecular Weight	142.56 g/mol
Synonyms	(4-Chloropyrimidin-2-yl)methanamine; 2-(Aminomethyl)-4-chloropyrimidine; 4-Chloro-2-pyrimidinylmethanamine; 1-(4-Chloro-2-pyrimidinyl)methanamine; 4-Chloro-2-(aminomethyl)pyrimidine; 2-Aminomethyl-4-chloropyrimidine; 4-Chloro-2-pyrimidinemethanamine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloropyrimidin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and commercial projects requiring material that meets internal quality standards or specific regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.