Description

5-Bromopyrimidine-2-Carboxaldehyde is a versatile and high-value brominated pyrimidine building block essential for advanced organic synthesis. This compound is particularly valued for its reactive aldehyde group, which enables efficient derivatization and incorporation into complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key precursor in the development of active pharmaceutical ingredients (APIs), ligands, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Bromopyrimidine-2-Carboxaldehyde
CAS No.	944902-05-0
Molecular Formula	C5H3BrN2O
Molecular Weight	186.99 g/mol
Synonyms	2-Pyrimidinecarboxaldehyde, 5-bromo-; 5-Bromo-2-formylpyrimidine; 5-Bromo-2-pyrimidinecarboxaldehyde; 5-Bromopyrimidine-2-carbaldehyde; 944902-05-0; 5-Bromopyrimidine-2-carboxaldehyde; 5-Bromo-2-pyrimidinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromopyrimidine-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply grades that meet the stringent requirements of cGMP manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep the container sealed under an inert gas such as nitrogen or argon for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.