Description

4-Chloro-5,6,7,8-tetrahydro-2-(methylthio)pyrido[4,3-d]pyrimidine is a high-value, heterocyclic organic compound serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fused pyrido-pyrimidine scaffold makes it a versatile building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutic agents targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds and probes to study enzyme function and cellular signaling.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Potential intermediate in the development of new herbicides or fungicides, leveraging its heterocyclic structure.

Basic Information

Product Name	4-Chloro-5,6,7,8-tetrahydro-2-(methylthio)pyrido[4,3-d]pyrimidine
CAS No.	944902-03-8
Molecular Formula	C10H12ClN3S
Molecular Weight	241.74 g/mol
Synonyms	4-Chloro-2-(methylthio)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 2-(Methylthio)-4-chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 4-Chloro-2-methylsulfanyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 4-Chloro-2-(methylsulfanyl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 4-Chloro-2-(methylmercapto)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; CAS 944902-03-8; Pyrido[4,3-d]pyrimidine, 4-chloro-5,6,7,8-tetrahydro-2-(methylthio)-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5,6,7,8-tetrahydro-2-(methylthio)pyrido[4,3-d]pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify specifications and confirm the absence of critical contaminants.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.