Description

2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is a versatile and high-value heterocyclic building block, specifically a chlorinated tetrahydropyridopyrimidine derivative. Its molecular scaffold is of significant interest for its role as a key synthetic intermediate in advanced organic synthesis. This compound is primarily sought after by research and development teams within the pharmaceutical and agrochemical sectors. Its structure makes it a critical precursor for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Organic Synthesis: Acts as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental research and custom synthesis projects.

Basic Information

Product Name	2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
CAS No.	944901-59-1
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 2-Chloro-5,6,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidine; 4H-Pyrido[4,3-d]pyrimidine, 2-chloro-5,6,7,8-tetrahydro-; 2-Chloro-4,5,6,7-tetrahydro-pyrido[4,3-d]pyrimidine (alternate numbering); Pyrido[4,3-d]pyrimidine, 2-chloro-5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous quality control ensures a reliable supply for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.