Description

2-Pyrrolidin-1-Yl-Pyrimidine-4-Carbaldehyde is a versatile heterocyclic aldehyde building block with significant utility in advanced organic synthesis. This compound is valued for its bifunctional reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Medicinal Chemistry Scaffold: Used to create diverse compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for metal catalysis and organocatalysts.
• Material Science Research: Used as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Chemical Biology Probes: Facilitates the creation of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Pyrrolidin-1-Yl-Pyrimidine-4-Carbaldehyde
CAS No.	944901-16-0
Molecular Formula	C9H11N3O
Molecular Weight	177.20 g/mol
Synonyms	2-(1-Pyrrolidinyl)-4-pyrimidinecarboxaldehyde; 4-Pyrimidinecarboxaldehyde, 2-(1-pyrrolidinyl)-; 2-(Pyrrolidin-1-yl)pyrimidine-4-carbaldehyde; 2-Pyrrolidin-1-ylpyrimidine-4-carbaldehyde; 2-(N-Pyrrolidino)pyrimidine-4-carboxaldehyde; Pyrrolidin-1-yl-pyrimidine-4-carbaldehyde; 944901-16-0; 2-Pyrrolidin-1-yl-4-pyrimidinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidin-1-Yl-Pyrimidine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.