Description

2-(Trifluoromethyl)Pyrimidine-4-Carbaldehyde is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. This compound is prized for its trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for creating specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and diagnostic agents due to its reactive aldehyde functionality.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex heterocyclic systems.

Basic Information

Product Name	2-(Trifluoromethyl)Pyrimidine-4-Carbaldehyde
CAS No.	944900-29-2
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	4-Pyrimidinecarboxaldehyde, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-pyrimidinecarbaldehyde; 2-Trifluoromethylpyrimidine-4-carboxaldehyde; 4-Formyl-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)-4-formylpyrimidine; 2-TFM-Pyrimidine-4-carbaldehyde; 2-CF3-Pyrimidine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Pyrimidine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.